Analgin / Metamizole Sodium

Product Overview

Analgin / Metamizole Sodium is a potent analgesic, antipyretic, and spasmolytic agent widely used in human medicine for moderate to severe pain. It is a prodrug that hydrolyzes to active metabolites with central and peripheral analgesic effects.

Metamizole acts via multiple mechanisms including COX inhibition and interaction with the opioid and endocannabinoid systems. Its spasmolytic properties make it particularly useful for colic and visceral pain, distinguishing it from other analgesics. It is available in oral, injectable, and suppository formulations.

Quality Specifications

Purity	As per CPV monograph
Residual Solvents	Compliant with ICH Q3C
Heavy Metals	Compliant with pharmacopoeia limits
GMP Status	Manufactured under GMP conditions

Pharmaceutical Applications

• Acute severe pain management: Moderate to severe acute pain of various origins
• Postoperative pain: Effective analgesia after surgical procedures
• Renal and biliary colic: Spasmolytic effect for visceral pain
• Cancer pain: Adjunct therapy for breakthrough cancer pain
• Fever refractory to other antipyretics: When paracetamol and NSAIDs are ineffective