Quick Facts
| CAS Number | 5907-38-0 (Sodium) / 68-89-3 (Metamizole) |
|---|---|
| Molecular Formula | C13H16N3NaO4S · H2O |
| Molecular Weight | 333.34 (Sodium salt monohydrate) |
| Pharmacopoeia | CPV, EP |
| Packaging | 25 KG/DRUM |
EP/BP Standard
GMP Certified
Product Overview
Analgin / Metamizole Sodium (Pharma Grade) is a potent analgesic, antipyretic, and spasmolytic agent widely used in human medicine for moderate to severe pain. It is a prodrug that hydrolyzes to active metabolites with central and peripheral analgesic effects.
Metamizole acts via multiple mechanisms including COX inhibition and interaction with the opioid and endocannabinoid systems. Its spasmolytic properties make it particularly useful for colic and visceral pain, distinguishing it from other analgesics. It is available in oral, injectable, and suppository formulations.
Quality Specifications
| Purity | As per CPV monograph |
|---|---|
| Residual Solvents | Compliant with ICH Q3C |
| Heavy Metals | Compliant with pharmacopoeia limits |
| GMP Status | Manufactured under GMP conditions |
Pharmaceutical Applications
- Acute severe pain management: Moderate to severe acute pain of various origins
- Postoperative pain: Effective analgesia after surgical procedures
- Renal and biliary colic: Spasmolytic effect for visceral pain
- Cancer pain: Adjunct therapy for breakthrough cancer pain
- Fever refractory to other antipyretics: When paracetamol and NSAIDs are ineffective