Quick Facts
| CAS Number | 51-05-8 |
|---|---|
| Molecular Formula | C13H20N2O2 · HCl |
| Molecular Weight | 272.77 |
| Pharmacopoeia | USP/BP/EP |
| Packaging | 25 KG/DRUM |
USP Standard
EP/BP Standard
GMP Certified
Product Overview
Procaine HCL is a local anesthetic of the amino ester class. It is the oldest synthetic local anesthetic still in clinical use and remains an important pharmaceutical API in human medicine.
Procaine blocks sodium ion channels in neuronal membranes, preventing the generation and conduction of nerve impulses and thereby blocking pain signal transmission. It is often combined with penicillin G (procaine penicillin) to provide prolonged antibiotic action. It is metabolized by plasma esterases, giving it a relatively short duration of action compared to amide-type anesthetics.
Quality Specifications
| Purity | As per USP monograph |
|---|---|
| Residual Solvents | Compliant with ICH Q3C |
| Heavy Metals | Compliant with pharmacopoeia limits |
| GMP Status | Manufactured under GMP conditions |
Pharmaceutical Applications
- Local anesthesia: Minor surgical procedures and wound suturing
- Dental anesthesia: Nerve block and infiltration anesthesia
- Procaine penicillin G preparations: Long-acting antibiotic formulations
- Diagnostic nerve blocks: Pain diagnosis and management
Standards: EP | CAS: 51-05-8 | Quality data verified against pharmacopoeia monograph
COA and MSDS available | DrugBank | July 2026