Phthalylsulfathiazole (Pharma Grade)

Product Overview

Phthalylsulfathiazole (Pharma Grade) is a sulfonamide antibiotic specifically designed for local intestinal antibacterial action in human medicine. It is poorly absorbed from the gastrointestinal tract, allowing it to achieve high local concentrations while minimizing systemic exposure.

Phthalylsulfathiazole is a prodrug that is hydrolyzed by intestinal enzymes in the large intestine to release the active sulfathiazole. This targeted delivery mechanism minimizes systemic absorption and maximizes local antibacterial effect in the gut, making it ideal for gastrointestinal infections and preoperative bowel preparation.

Quality Specifications

Purity	As per USP monograph
Residual Solvents	Compliant with ICH Q3C
Heavy Metals	Compliant with pharmacopoeia limits
GMP Status	Manufactured under GMP conditions

Pharmaceutical Applications

• Intestinal antisepsis: Reduction of intestinal bacterial flora
• Preoperative bowel preparation: Reducing surgical site infection risk in colorectal surgery
• Bacterial dysentery: Treatment of bacillary dysentery
• Inflammatory bowel disease adjunct therapy: Reducing bacterial overgrowth in IBD
• Gastrointestinal infections: Bacterial enteritis and colitis