Quick Facts
| CAS Number | 85-73-4 |
|---|---|
| Molecular Formula | C17H13N3O5S2 |
| Molecular Weight | 403.44 |
| Pharmacopoeia | BP |
| Packaging | 25 KG/DRUM |
USP Standard
EP/BP Standard
GMP Certified
Product Overview
Phthalylsulfathiazole is a sulfonamide antibiotic specifically designed for local intestinal antibacterial action in human medicine. It is poorly absorbed from the gastrointestinal tract, allowing it to achieve high local concentrations while minimizing systemic exposure.
Phthalylsulfathiazole is a prodrug that is hydrolyzed by intestinal enzymes in the large intestine to release the active sulfathiazole. This targeted delivery mechanism minimizes systemic absorption and maximizes local antibacterial effect in the gut, making it ideal for gastrointestinal infections and preoperative bowel preparation.
Quality Specifications
| Purity | As per USP monograph |
|---|---|
| Residual Solvents | Compliant with ICH Q3C |
| Heavy Metals | Compliant with pharmacopoeia limits |
| GMP Status | Manufactured under GMP conditions |
Pharmaceutical Applications
- Intestinal antisepsis: Reduction of intestinal bacterial flora
- Preoperative bowel preparation: Reducing surgical site infection risk in colorectal surgery
- Bacterial dysentery: Treatment of bacillary dysentery
- Inflammatory bowel disease adjunct therapy: Reducing bacterial overgrowth in IBD
- Gastrointestinal infections: Bacterial enteritis and colitis
Standards: BP | CAS: 85-73-4 | Quality data verified against pharmacopoeia monograph
COA and MSDS available | DrugBank | July 2026