Lincomycin HCL

Product Overview

Lincomycin HCL is a lincosamide antibiotic produced by Streptomyces lincolnensis. It is primarily active against Gram-positive bacteria and anaerobes, and serves as an important alternative for penicillin-allergic patients in human medicine.

Lincomycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. It is often used in combination with other antibiotics for polymicrobial infections. It achieves excellent bone concentration, making it a valuable option for bone and joint infections.

Quality Specifications

Purity	As per USP monograph
Residual Solvents	Compliant with ICH Q3C
Heavy Metals	Compliant with pharmacopoeia limits
GMP Status	Manufactured under GMP conditions

Pharmaceutical Applications

• Serious Gram-positive infections: Staphylococcal and streptococcal infections
• Anaerobic infections: Including Bacteroides and Clostridium infections
• Penicillin-allergic patients: Alternative to penicillin and cephalosporins
• Bone and joint infections: Osteomyelitis and septic arthritis
• Dental infections: Odontogenic abscesses and periodontitis