Quick Facts
| CAS Number | 859-18-7 (HCl) / 154-21-2 (Base) |
|---|---|
| Molecular Formula | C18H34N2O6S · HCl · H2O |
| Molecular Weight | 461.02 (HCl monohydrate) |
| Pharmacopoeia | USP/ EP/ CEP/IN HOUSE |
| Packaging | 25 KG/DRUM |
USP Standard
EP/BP Standard
GMP Certified
Product Overview
Lincomycin HCl (Pharma Grade) is a lincosamide antibiotic produced by Streptomyces lincolnensis. It is primarily active against Gram-positive bacteria and anaerobes, and serves as an important alternative for penicillin-allergic patients in human medicine.
Lincomycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. It is often used in combination with other antibiotics for polymicrobial infections. It achieves excellent bone concentration, making it a valuable option for bone and joint infections.
Quality Specifications
| Purity | As per USP monograph |
|---|---|
| Residual Solvents | Compliant with ICH Q3C |
| Heavy Metals | Compliant with pharmacopoeia limits |
| GMP Status | Manufactured under GMP conditions |
Pharmaceutical Applications
- Serious Gram-positive infections: Staphylococcal and streptococcal infections
- Anaerobic infections: Including Bacteroides and Clostridium infections
- Penicillin-allergic patients: Alternative to penicillin and cephalosporins
- Bone and joint infections: Osteomyelitis and septic arthritis
- Dental infections: Odontogenic abscesses and periodontitis