Clotrimazole

Product Overview

Clotrimazole is a broad-spectrum imidazole antifungal agent used for treating dermatophyte infections, candidiasis, and other fungal conditions. It is available in various topical formulations.

Clotrimazole inhibits fungal ergosterol biosynthesis by blocking lanosterol 14α-demethylase, disrupting fungal cell membrane integrity. It is effective against dermatophytes, yeasts, and some Gram-positive bacteria.

Quality Specifications

Purity	As per USP monograph
Residual Solvents	Compliant with ICH Q3C
Heavy Metals	Compliant with pharmacopoeia limits
GMP Status	Manufactured under GMP conditions

Applications

• Vulvovaginal candidiasis:
• Dermatophytosis: ringworm
• Oral thrush:
• Athlete's foot:
• Topical antifungal creams and suppositories: