Quick Facts
| CAS Number | 81103-11-9 |
|---|---|
| Molecular Formula | C38H69NO13 |
| Molecular Weight | 748 |
| Pharmacopoeia | EP/USP/IP/CP |
| Packaging | 25 KG/DRUM |
USP Standard
EP/BP Standard
Product Overview
Clarithromycin is a semi-synthetic macrolide antibiotic derived from erythromycin. It offers improved acid stability, better oral absorption, and broader antimicrobial activity compared to erythromycin.
Clarithromycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. Its 14-hydroxy metabolite is also microbiologically active, contributing to its effectiveness against H. influenzae.
Quality Specifications
| Purity | As per USP monograph |
|---|---|
| Residual Solvents | Compliant with ICH Q3C |
| Heavy Metals | Compliant with pharmacopoeia limits |
| GMP Status | Manufactured under GMP conditions |
Applications
- H. pylori eradication: triple therapy
- Community-acquired pneumonia:
- Upper respiratory infections:
- Mycobacterium avium complex: MAC
- Skin and soft tissue infections: