Ciprofloxacin is a second-generation fluoroquinolone with potent Gram-negative activity, frequently deployed in veterinary medicine for severe enteric and systemic infections in poultry, swine, and aquaculture. Its concentration-dependent bactericidal action and high oral bioavailability make it a go-to choice for flock-level medication programs.
Quick Facts
| CAS Number | 85721-33-1 / 86393-32-0 (HCl) |
|---|---|
| Molecular Formula | C17H18FN3O3 (Base) |
| Molecular Weight | 331.34 (Base) / 385.82 (HCl) |
| Pharmacopoeia | USP/EP (Base) / EP/USP/IP/CP (HCl) |
| Packaging | 25 KG/DRUM |
Product Overview
Ciprofloxacin is a second-generation fluoroquinolone antibiotic for veterinary use, offering broad-spectrum bactericidal activity against both Gram-negative and Gram-positive organisms. It is one of the most potent fluoroquinolones against Gram-negative bacteria including Pseudomonas aeruginosa, making it highly valuable in veterinary medicine.
Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication. Its excellent tissue penetration makes it effective for deep-seated and intracellular infections. Available as both base (for oral suspensions) and hydrochloride salt (for tablets and injections). Widely used in poultry, swine, cattle, and aquaculture.
Quality Specifications
| Purity | As per USP monograph |
|---|---|
| Residual Solvents | Compliant with ICH Q3C |
| Heavy Metals | Compliant with pharmacopoeia limits |
| GMP Status | Manufactured under GMP conditions |
Veterinary Applications
- Poultry colibacillosis and fowl cholera: Treatment of E. coli and Pasteurella multocida infections
- Swine respiratory and enteric infections: Management of bacterial pneumonia and diarrhea
- Bovine mastitis and pneumonia: Intramammary and parenteral therapy in cattle
- Fish bacterial diseases (Aeromonas, Vibrio): Aquaculture applications for systemic infections
- Companion animal UTIs and skin infections: Treatment of urinary tract and dermatological infections