Enrofloxacin HCl

Product Overview

Enrofloxacin Hydrochloride is the hydrochloride salt of enrofloxacin, a fluoroquinolone antibiotic developed specifically for veterinary use. As the HCl salt form, it offers enhanced water solubility compared to the base form, making it particularly suitable for oral solution and drinking water formulations. It exerts its bactericidal effect by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication.

Enrofloxacin HCl demonstrates broad-spectrum bactericidal activity against both Gram-negative bacteria (including E. coli, Salmonella, Pasteurella, and Actinobacillus) and Gram-positive bacteria, as well as against Mycoplasma species and intracellular pathogens such as Brucella and Chlamydia. Its excellent bioavailability and extensive tissue penetration allow it to reach therapeutic concentrations in the respiratory tract, urinary tract, gastrointestinal tract, and skin. It is partially metabolized to ciprofloxacin in vivo, contributing to its sustained antimicrobial effect.

Quality Specifications

Purity	As per IN HOUSE standard
Water Content	Controlled per specification
Heavy Metals	Compliant with pharmacopoeia limits
GMP Status	Manufactured under GMP conditions

Veterinary Applications

Therapeutic Areas

• Poultry: Respiratory infections, colibacillosis, mycoplasmosis
• Swine: Bacterial enteritis, respiratory infections
• Cattle: Bovine respiratory disease (BRD), pneumonia
• Companion Animals: Skin infections, UTIs, respiratory infections