Tilmicosin Phosphate

Product Overview

Tilmicosin Phosphate is a semi-synthetic 16-membered macrolide antibiotic phosphate salt developed specifically for veterinary use. It is derived from tylosin and was designed to provide a long-acting formulation with preferential accumulation in lung tissue. This pharmacokinetic property makes it particularly effective against respiratory tract infections in livestock.

Tilmicosin is highly effective against key respiratory pathogens including Pasteurella multocida, Mannheimia haemolytica, Actinobacillus pleuropneumoniae, Mycoplasma bovis, and Mycoplasma hyopneumoniae. Its mechanism of action involves binding to the 50S ribosomal subunit, inhibiting bacterial protein synthesis. The phosphate salt form is designed for incorporation into feed premixes, allowing for mass medication via oral administration. Tilmicosin's extended tissue half-life provides sustained therapeutic concentrations at the site of infection, reducing the frequency of dosing and improving treatment outcomes.

Quality Specifications

Purity	As per IN HOUSE standard
Residual Solvents	Compliant with ICH Q3C
Heavy Metals	Compliant with pharmacopoeia limits
GMP Status	Manufactured under GMP conditions

Veterinary Applications

Therapeutic Areas

• Cattle: Bovine respiratory disease (BRD), Pasteurella and Mannheimia infections
• Swine: Respiratory disease complex, mycoplasmal pneumonia, pleuropneumonia
• Sheep: Ovine respiratory infections, pasteurellosis
• Poultry: Mycoplasma infections, respiratory disease