Quick Facts

CAS Number	73231-34-2
Molecular Formula	C₁₂H₁₄Cl₂FNO₄S
Molecular Weight	358.21
Pharmacopoeia	CVP, IN HOUSE
Packaging	25 KG/DRUM

GMP Certified

Product Overview

Florfenicol is a broad-spectrum fluorinated thiamphenicol antibiotic developed specifically for veterinary use. It is a structural analog of thiamphenicol where the hydroxyl group is replaced by a fluorine atom, conferring resistance to bacterial acetylation and thus overcoming chloramphenicol resistance mechanisms.

Florfenicol demonstrates potent bactericidal activity against a wide range of Gram-positive and Gram-negative bacteria, including strains resistant to chloramphenicol and thiamphenicol. It is particularly effective against Pasteurella multocida, Mannheimia haemolytica, Actinobacillus pleuropneumoniae, and various aquatic pathogens. Its excellent tissue penetration and broad-spectrum activity make it a first-line antibiotic in aquaculture, poultry, and livestock production systems worldwide.

Quality Specifications

Purity	As per CVP/IN HOUSE monograph
Residual Solvents	Compliant with ICH Q3C
Heavy Metals	Compliant with pharmacopoeia limits
GMP Status	Manufactured under GMP conditions

Veterinary Applications

Aquaculture

Widely used in fish and shrimp farming for control of bacterial infections including furunculosis, vibriosis, and streptococcosis. Administered via medicated feed.

Bovine Respiratory Disease

First-line treatment for BRD in cattle caused by Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni. Injectable formulation with excellent lung penetration.

Therapeutic Areas

Aquaculture: Bacterial infections in fish and shrimp, furunculosis, vibriosis
Cattle: Bovine respiratory disease (BRD), pneumonia
Swine: Respiratory disease, bacterial pneumonia
Poultry: Bacterial infections, colibacillosis

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