Captopril

Product Overview

Captopril is the first orally active angiotensin-converting enzyme (ACE) inhibitor. It revolutionized the treatment of hypertension and heart failure when introduced, and remains an important cardiovascular medication.

Captopril inhibits ACE, preventing the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. This leads to vasodilation, reduced aldosterone secretion, and decreased blood pressure.

Quality Specifications

Purity	As per USP monograph
Residual Solvents	Compliant with ICH Q3C
Heavy Metals	Compliant with pharmacopoeia limits
GMP Status	Manufactured under GMP conditions

Applications

• Hypertension management:
• Congestive heart failure:
• Post-myocardial infarction therapy:
• Diabetic nephropathy prevention: