Tylosin Phosphate

Product Overview

Tylosin Phosphate is a macrolide antibiotic phosphate salt derived from Streptomyces fradiae. It is a 16-membered macrolide lactone with broad-spectrum activity against Gram-positive bacteria, mycoplasma species, and certain Gram-negative organisms. As the phosphate salt form, it is primarily designed for incorporation into animal feed as a premix for prophylactic and growth-promoting purposes.

Tylosin Phosphate acts by binding to the 50S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis. It is highly effective against Mycoplasma gallisepticum, Mycoplasma synoviae, Mycoplasma hyopneumoniae, and other veterinary mycoplasma species. In addition to its antibacterial activity, tylosin has been shown to have immunomodulatory and anti-inflammatory effects. As a feed additive, Tylosin Phosphate has a long history of safe and effective use in improving feed efficiency, promoting weight gain, and reducing the incidence of chronic respiratory disease in poultry and swine dysentery.

Quality Specifications

Purity	As per CVP monograph
Residual Solvents	Compliant with ICH Q3C
Heavy Metals	Compliant with pharmacopoeia limits
GMP Status	Manufactured under GMP conditions

Veterinary Applications

Therapeutic Areas

• Poultry: Chronic respiratory disease (CRD), mycoplasma infections
• Swine: Swine dysentery, mycoplasmal pneumonia, growth promotion
• Livestock: Mycoplasma infections, feed additive for growth promotion